KNOWING MORE CAN GIVE YOU MORE WAYS TO FIGHT.

Genetic COPD is a condition called alpha-1 antitrypsin deficiency (AATD), also referred to as alpha-1. It is passed from parents to their biological children.^1–2 Alpha-1 may lead to various health conditions. Most commonly, it leads to lung disease.

Alpha-1 is caused by certain genetic variants in the SERPINA1 gene. These variants cause low levels of a specific protein known as alpha-1 antitrypsin (AAT). AAT is released by the liver, enters the blood, and is transported to the lungs. AAT plays a critical role in safeguarding the lungs, so having low levels of AAT may cause lung disease that appears similar to traditional COPD.

Yes. While there is no cure for alpha-1, it is important to know that treatment options may be available.^*1,3-5 There are FDA-approved treatment options that may be right for you—ask your healthcare provider. The first step is to find out your risk for alpha-1 using the easy AlphaID At Home Genetic Health Risk Service.

t’s important to know if your genetics play a role in your COPD. It’s never been easier to learn your risk with a free, at-home screening kit.^† For some people diagnosed with alpha-1, FDA-approved treatment options may be available to consider with your healthcare provider.^*

COPD can be caused by smoking, secondhand smoke, or exposure to harmful environmental factors.6 However, for some, it is also due to a hereditary condition known as alpha-1, which may lead to serious lung disease. Whether you are a smoker, a former smoker, or have never smoked at all, you could have alpha-1 since it is inherited from your biological parents. According to the COPD Foundation, the World Health Organization, the American Thoracic Society, and the GOLD COPD guidelines, if you have been diagnosed with COPD, you should get screened for alpha-1.^{1, 3–5}

For many people, COPD is caused by smoking, secondhand smoke, or exposure to harmful environmental factors,⁶ but for some, it also may be due to a genetic condition. Smokers and nonsmokers alike can have alpha-1. Because the symptoms of alpha-1 are the same as traditional COPD symptoms, alpha-1 can go undetected for years. In fact, more than 90% of the estimated 100,000 people in the United States who have alpha-1 don't know they have it.^7-8

The good news is that it’s never been easier to be screened for alpha-1. The FDA-cleared AlphaID™ At Home Saliva Collection Kit has the supplies you need to find out your risk for alpha-1 with at least 99% accuracy. Simply provide a saliva sample—you can do it right from home. Learn More

There are a few ways. The FDA-cleared AlphaID At Home Genetic Health Risk Service makes it easy to find out your risk for alpha-1 from the comfort and convenience of your own home. The kit has all the supplies you need to collect a small saliva sample and mail it to the lab. The kit and the lab processing are free—no payment or insurance information will be required at any time. AlphaID™ At Home is an FDA-cleared service that detects 14 variants in the SERPINA 1 gene linked to alpha-1 with at least 99% accuracy.

Other options for alpha-1 screening and testing include making an appointment with your healthcare professional, who may use another screener or request a blood test through a commercial lab (eg, LabCorp, Quest). You could also buy another at-home service or genetic test kit.

Whichever method you choose, it is important to know your risk for alpha-1. If you decide not to use the AlphaID At Home Genetic Health Risk Service, be sure to check with your insurance company to understand the costs associated with going to a commercial lab.

The AlphaID At Home Genetic Health Risk Service is a free and easy way to learn your risk for a genetic COPD, a condition called alpha-1 antitrypsin deficiency (AATD), also commonly referred to as alpha-1.^† It is the only FDA-cleared genetic health risk service that detects 14 variants in the SERPINA1 gene linked to alpha-1 with at least 99% accuracy.

Simply collect a small saliva sample by swabbing along your gumline, from the comfort of your home to determine your risk.

Yes. The AlphaID At Home Genetic Health Risk Service is at least 99% accurate and is FDA-cleared.

To receive FDA clearance, a product goes through a rigorous process to make sure that it is safe, accurate, and clear for the consumer to understand.

After reviewing all the information about the AlphaID At Home Genetic Health Risk Service and AlphaID™ At Home Saliva Collection Kit, the FDA cleared the Service and kit for US consumers over 18 years old to learn their risk for alpha-1 on their own.

The FDA provided clearance through Premarket Notification 510(k). If you would like to read more information about this process, click here: Direct-to-Consumer Tests | FDA and Premarket Notification 510(k) | FDA  

Yes. The AlphaID At Home Genetic Health Risk Service, including the kit, is provided for free and may not be billed to patients or their insurers. The AlphaID™ At Home Saliva Collection Kit contains all the supplies you need to collect and mail your saliva sample. The kit, postage, and lab processing are all free—no payment or insurance information will be required at any time. Order your free kit today.

Your AlphaID At Home Saliva Collection Kit has the supplies you need to find out your risk for developing lung disease linked to alpha-1. Inside your kit, you will find:

• Instructions for Use
• Bio-specimen bag
• Saliva collection device with your unique barcode
• Record card with your unique barcode
• Postage-paid mailer box to mail your sample to the third party lab

To learn more about the AlphaID At Home Saliva Collection Kit and AlphaID At Home Genetic Health Risk Service, visit AlphaIDAtHome.com.

It is important to register your kit, collect your sample, and return it as soon as possible. Knowing your risk for alpha-1 should not wait. Make sure to collect and return your sample within 60 days of receiving your kit.

Grifols takes your privacy very seriously and complies with all applicable HIPAA guidelines and privacy laws to safeguard the personal information you share on this website or via the AlphaID At Home Genetic Health Risk Service. Grifols has set up a secure, password-protected customer website where you can access your AlphaID™ At Home Genetic Health Risk Service Report. Grifols will not have access to your report or any specific information contained in it. Read our full privacy policy.  

Although the Service was designed to be easy for you to learn your risk at home for alpha-1, we realize you may have questions about the process. If you don’t find what you’re looking for on AlphaIDAtHome.com, please reach out to our Customer Support Team at 1-844-891-3030. A live Customer Support Team member will be available Monday–Friday, 8 AM - 8 PM ET and Saturday, 9 AM - 3 PM ET. If you call outside of those hours, you can leave a voicemail and a team member will return your call within one business day.

Grifols is a leading global healthcare company founded in Barcelona, Spain, with more than 110 years of history improving the health and well-being of people around the world. Grifols provides innovative healthcare solutions and services and has been a trusted market leader in alpha-1 antitrypsin deficiency testing for over 20 years. The company has a presence in more than 30 countries and regions, including corporate offices located in California and North Carolina. If you’re interested in learning more, please visit www.grifols.com.

For many people, chronic obstructive pulmonary disease (COPD) can be caused by smoking, secondhand smoke, or environmental factors,6 like working with chemicals and other harmful substances that are breathed in on a regular basis. But for some people, COPD is actually caused by genetic COPD, also known as alpha1-antitrypsin deficiency (AL-fa / one / an-tee-TRIP-sin / de-FISH-an-see), or alpha-1. Both smokers and nonsmokers alike can have alpha-1 because it is inherited.

The AlphaID At Home Genetic Health Risk Service is a free and easy way to learn your risk for alpha-1.^† It is the only free, FDA-cleared genetic health risk service that detects 14 variants in the SERPINA1 gene linked to alpha-1 with at least 99% accuracy. Of course, you should also always consult with your healthcare professional if you have any questions about COPD or how to help COPD. They can also tell you about potential treatment options for COPD and/or alpha-1.

Yes. According to the COPD Foundation, the World Health Organization, the American Thoracic Society, and the GOLD COPD guidelines, if you have been diagnosed with COPD, you should get screened for alpha-1.^1,3–5

With the AlphaID At Home Genetic Health Risk Service, it’s free and easy to take the first step in finding out your risk for alpha-1.^†

The COPD Foundation is a not-for-profit organization established to speed innovations that will make treatments more effective and affordable, undertake initiatives that result in expanded services for COPD patients, and improve the lives of patients with COPD. https://www.copdfoundation.org ^‡